Clinical studies show taking Flavay significantly improves (both objectively and subjectively) recovery from glare and sensitivity to light when working at computers and in driving at night.

Protect Your Eyes from Computer LED Blue Light and Digital Eye Strain

Recovery from Glare and Night Vision

Light-sensitivity ∙ Recovery from glare ∙ Light-dark adaptations ∙ Driving at Night ∙ Digital eye strain ∙ Computer vision syndrome

Clinical studies show taking Flavay® significantly improves (both objectively and subjectively) recovery from glare and sensitivity to light when working at computers and in driving at night. (63,64,65,71,262,263)
Chart shows 98 out of 100 found significant improvement in visual performance in the dark after glare after taking Flavay.
A multi-center study of 100 people with healthy eyes found decreased vision in people working at a computer monitor or driving at night. After 4 weeks of taking Flavay® (200 mg per day), 98 out of 100 participants showed “significant improvement” in visual performance in response and sensitivity to light, recovery from glare and night vision. (63)
Chart shows 72 out of 91, 79% of subjects, found objective improvement in retinal sensitivity in the dark after glare after taking Flavay.
In a study of 91 persons with bilateral myopia and associated ocular disorders, objective testing found taking Flavay® (300 mg daily for 30 days) resulted in improvement in retinal sensitivity and recovery after glare in 72 subjects (79%). (262)
Chart shows 72 out of 91, 79% of subjects, found objective improvement in retinal sensitivity in the dark after glare after taking Flavay.
Subjective improvement in retinal sensitivity and recovery after glare was even greater, with 90% of subjects reporting symptom improvement with Flavay®. (262)
Clinical trials show taking Flavay® (200-to-300 mg daily for 30-60 days) improves retinal sensitivity to light and recovery after glare. (63,64,65,71,262,263)

A multi-center study of 100 subjects without major ocular pathology who daily sit in front of computer monitors or drive at night were tested taking 200mg per day of Flavay®. After five weeks their vision was measured for resistance to blinding light, and in dim light. The group receiving Flavay® demonstrated significant improvements in dark vision and in visual response to glare. (63)

In a French study of 100 healthy volunteers, those who received Flavay® (200 mg daily for six weeks) had a marked improvement in dark vision and recovery from glare. (64)

An Italian study of 91 subjects with bilateral myopia and associated ocular disorders demonstrated that taking Flavay® (300 mg daily for 30 days) resulted in improvement in retinal sensitivity during dark adaptation in 72 subjects (79%). Subjective improvement was even greater, with 90% of subjects reporting improvement in retinal sensitivity and recovery after glare after taking Flavay®. (262)

A double-blind study of 40 myopic subjects found those taking Flavay® (150 mg per day for 30 days) demonstrated significant improvement compared to the placebo group. Significant electro-retinographic improvements were noted in 40% (8 subjects) in the Flavay® group and none (0 subjects) in the placebo group. (65)

In a randomized, double-blind, placebo-controlled study of 75 subjects experiencing visual stress from video-display units found that Flavay®, (300 mg per day for 60 days) resulted in significant improvement in contrast sensitivity and subjective visual disturbances. (263)

An open study measured the effects of Flavay® on 26 subjects with retinopathy and capillary fragility, microaneurysms, exudates and hemorrhages. Capillary fragility (measured with Parrot’s angiosterrometer) improved in 11 subjects, condition of the ocular fundus improved in 15 subjects, and overall improvement in 21 subjects was reported. (250)

In human trials, Flavay® is shown to reduce pressure in ophthalmic membranes by preventing abnormal leakage of fluids into the orbital cavity and tissues and thereby slow down progression of retinopathies. Flavay® seals leaky capillaries, strengthens vessels and prevents outflow of blood or liquid. The number of microbleedings in retinal tissue is thereby reduced and visual acuity can improve. (249,250)

A review of 26 human studies reveals Flavay® significantly improved vascular lesions, microaneurysms, and exudates associated with diabetic retinopathy. (71)

The effects of Flavay® (100 mg per day) were measured on 147 persons with retinopathy. Flavay® improved all cases of exudations linked to ischemia (inadequate blood supply) linked to a diabetic, ateriosclerotic, inflammatory, degenerative and myopic nature. (69)

The effects of Flavay® (150 mg per day) were measured on 30 retinopathy subjects who suffered from microaneurysms, hemorrhages, exudations and neovascularization after capillary hypoxia. Retinal infectional lesions were stabilized in 80% of persons taking Flavay®. (72)

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Flavay® Protects Retinal Cells From Oxidation

Oxidative stress is a major cause of cell death and the hallmark of optic neurodegenerative diseases (including retinopathy and glaucoma) is retinal ganglion cell-death. (257-259,299)

Studies show Flavay® protects oxidative stress-injured retinal ganglion cells by inhibiting apoptosis (death). (328,329)

Our body's antioxidant mechanisms become progressively less effective as we age. A number of epidemiologic studies have found that persons with age-related eye diseases have significantly lower levels of antioxidants, particularly vitamin C, than persons who do not develop eye conditions. Research shows Flavay® increases intracellular vitamin C levels and dramatically extends the lifetime of vitamin C in the human body. Also, Flavay® provides its own powerful antioxidant protection to the eyes and its tiny blood vessels, and Flavay® enhances the protective effect of vitamin E and supports an important activity of vitamin A in human eyes. (1,81,63,64,71,202,260)

Light, Oxidation and Vision Loss

Due to the exposure to sunlight and high oxygen concentration, the oxidative stress burden is higher in the eye than other tissues, which can be further complicated by additional oxidative stressors such as smoke, smog, chemical pollution and chronic exposure to “blue light” digital radiation. (323-327)

It's been shown, through both animal and human studies, that oxygen and light generate free radicals or precursors and oxidative damage which plays a critical role in macular degeneration, glaucoma, retinal degeneration and retinopathies, and cataracts. (257-259,299)

diagram of eye shows cornea, lens, macula and retina, leaking blood vessels, macular edema (swelling in macula), blocked central retinal vein.
UV light induces oxidative stress to the front of the eye, and “blue” light reaches deeper into the eye where its cumulative oxidative stress can cause damage to the retina. (320-322,326)

Electronic devices, TVs, computers, laptops, smart phones and tablets, and fluorescent and LED lighting generate high-energy visible (HEV) or “blue light.” A recent Harvard Health Letter warns that chronic exposure to digital “blue light” may lead to macular degeneration, glaucoma, and retinal degenerative diseases which can eventually cause serious vision loss and blindness. (322)

Oxidative damage is responsible for macular degeneration, glaucoma, and retinal degenerative diseases which can eventually cause serious vision loss and blindness. (257-259,299)

diagram of eye shows cornea, lens, macula and retina, leaking blood vessels, macular edema (swelling in macula), blocked central retinal vein.
Oxidation damages collagen in vessels so the vessels become brittle and fragile. Bleeding, leaking, and scarring from the damaged vessels eventually cause vision loss. Extensive scientific and clinical studies show Flavay® strengthens collagen proteins and seals leaky capillaries, strengthens vessels and prevents outflow of blood or liquid. The number of microbleedings in retinal tissue is thereby reduced and visual acuity can improve when taking Flavay®. (249,250)

Flavay Methods of Action

Scientific and clinical studies show Flavay® significantly protects retinal tissue and vision in the following important ways:

Antioxidant and Anti-inflammatory Actions of Flavay. Recycles and improves activities of vitamin C, and protective effects of vitamin E and activity of vitamin A. Protects against lipid peroxidation damage. Highly reactive in both lipid (fat) and aqueous (water) phases of oxidation. Helps balance nitric oxide activity, both to stimulate normal synthesis and inhibit over-production of nitric oxide. Improves total antioxidant capacity and stimulates antioxidant defense systems. Superior antioxidant activity and DNA protection in studies comparing against vitamins C, E and beta carotene (vitamin A).

Antioxidant and Anti-inflammatory Actions of Flavay®

  • Flavay® is shown to increase an important function of vitamin A (rhodopsin regeneration) thereby improving visual performance in low light and in light-to-dark adaptations. (63,64,71)
  • The hallmark of optic neurodegenerative diseases (including retinopathy and glaucoma) is retinal ganglion cell-death. Studies show Flavay® protects oxidative stress-injured retinal ganglion cells by inhibiting apoptosis (cell-death). (257-259,299)
  • Nitric oxide is essential for normal blood circulation as it controls the muscular tone of blood vessels and regulates circulation and blood flow. However, nitric oxide is a free radical and excessive amounts of nitric oxide can contribute to optic neurodegenerative diseases. So, in order to have normal circulation and vision, the body must maintain the right balance of nitric oxide—and that's where Flavay® is shown to help. (10,239,265,292,296)
  • Nitric oxide plays a major role in the control of ocular blood flow as a potent endothelium-derived vasodilator. Flavay®'s nitric oxide activity improves circulation and blood flow in the eyes. (237-239)
  • Flavay® helps balance nitric oxide activity, both to stimulate normal synthesis and inhibit over-production of nitric oxide. (239,265,292,296)
  • Flavay® is shown to improve vasodilation and mildly inhibit angiotensin-converting enzyme (ACE) by modulating nitric oxide metabolism in endothelial cells. (292,296)
  • Regenerates (actually recycles) and improves intracellular activity of vitamin C and protective effects of vitamin E and activity of vitamin A. (83,33,274,276,63,64,71)
  • Protects against lipid peroxidation damage. Highly reactive in both lipid (fat) and aqueous (water) phases of oxidation. (277,283,284,299)
  • Improves total antioxidant capacity and stimulates antioxidant defense systems. (33,83,274,276)
  • Superior antioxidant activity and DNA protection in studies comparing against vitamins C, E and beta carotene (vitamin A). (272)
  • Helps increase synthesis of and intracellular levels of superoxide dismutase (Cu/Zn-SOD). (369,371,372,373)
  • Helps raise intracellular levels of glutathione peroxidase (GPx) including acetylcysteine and improves glutathione reductase activity. (Flavay® is found to improve intracellular glutathione status better than taking a glutathione supplement. Acetylcysteine is a precursor of glutathione in the body.) (361,366,368,369,371,373)
  • Protects against free radical release of histamine from mast cells. (35,56,78,146)
  • Inhibits pro-inflammatory cytokine actions. (18,25,61,74,81)
Flavay: International and U.S. Patents and Clinically Proven

Flavay® is patented as a scavenger of the free radicals that play a major role in the degradation of collagen and in the initiation, duration and breakdown of inflammation and in ischaemia (reduced blood flow).

“[A] method for preventing and fighting the harmful biological effects of free radicals in the organism of warm blooded animals and more especially human beings, namely cerebral involution, hypoxia following atherosclerosis, cardiac or cerebral infarction, tumour promotion, inflammation, ischaemia, alterations of the synovial liquid, collagen degradation, among others.”
—U.S. Patent No. 4,698,360 (1987).
diagram of eye shows cornea, lens, macula and retina, leaking blood vessels, macular edema (swelling in macula), blocked central retinal vein.
Flavay® seals leaky capillaries, strengthens vessels and prevents outflow of blood or liquid. The number of microbleedings in retinal tissue is thereby reduced and visual acuity can improve when taking Flavay®. (249,250)

In France, Flavay® is used to improve a variety of peripheral circulatory problems characterized by capillary fragility and impaired venous drainage. The vascular protective activity of Flavay® has been established by many significant studies. (44-48,270)

Flavay® is shown to increase capillary resistance, decrease capillary permeability, and increase rate of lymph flow. (47,48,82,205)

Research shows Flavay® improves strength and tone of veins, arteries, capillaries (the smallest vessels) and lymphoid tissues by strengthening the essential constituents in vascular walls (collagen and elastin). (47,48,82,205)

Flavay® reduces damaging effects of elastase, collagenase and hyaluronidase by altering membrane receptor conformation of vascular walls and preventing destructive enzymes from attaching to and degrading vascular walls. (23,67,268)

Flavay® further prevents destruction of vascular walls by preventing the attachment to membranes of histamine, which decreases strength of vessel walls. (35,56,77-79,87,146)

Flavay® is shown to strengthen collagen in three ways:

  1. NEW GROWTH of Collagen: Flavay® activates growth of strong and flexible collagen and elastin, the building blocks of vascular walls. Clinically proven to rebuild elasticity in blood vessels and skin, and to improve circulation—including micro-circulation in the smallest capillaries. (18,25,46,81,102,200,230,269,270,291)
  2. REACTIVATE Collagen: Flavay® is proven to reactivate, strengthen and rebuild damaged collagen. Flavay® strengthens collagen proteins as it supports adequate crosslinking and effectively fights the adverse biological conditions which result in over-crosslinking. Research demonstrates Flavay® binds to collagen fibers and realigns them to a more youthful form. Laboratory tests demonstrate Flavay’s® ability to reduce degradation of elastin fibers by up to 70 percent. Studies also show that pure vitamin C is less effective in synthesis of collagen when the phytonutrients of Flavay® are missing. (18,19,23,60,266-268)
  3. PROTECT Collagen: Flavay® binds tightly and protects collagen, elastin and hyaluronic acid from the destructive enzymes elastase, collagenase and hyaluronidase. Flavay® also inhibits cleavage of enzymes secreted during inflammation and infection, and prevents release and synthesis of compounds that promote inflammation (histamine, serine proteases, prostaglandins and leukotrienes). (18,25,61,74,81)
too much crosslinking in collagen polypeptides causes leaky vessels and saggy skin
Flavay® improves the beneficial crosslinking between amino acids of the fibers that give collagen its flexibility and strength while preventing the undesirable over-crosslinking that weakens collagen. Laboratory tests demonstrate Flavay’s® ability to reduce degradation of elastin fibers by up to 70%. (18,19,60)
Anti-inflammatory activity of Flavay: Flavay protects against unfavorable free-radical release of histamine. Cycle shows: 1 Free radical activator. 2 Flavay protects inactive hyaluronidase. 3 results in reduction of hyaluronidase activation. 4 which protects inactive histamine. 5 which reduces histamine activation. 6. which reduces inflammation and allergic response.
Flavay® lowers the inflammatory and allergic activity of histamine by protecting against free-radical activation of hyaluronidase. (3,35,56,78,146)
Hyaluronidase activation breaks also down hyaluronic acid in retinal tissue. Low levels of hyaluronic acid (known as hyaluronan) is a contributing factor in vitreous deterioration, retinal detachment and formation of macular holes. (376,377)

Several studies demonstrate Flavay® can inhibit activity of the enzyme histidine decarboxylase and found Flavay® lowered the production of histamine with as much as 86% by inhibition of histidine decarboxylase. One study found the anti-inflammation activity of Flavay® was twice as strong as phenylbutazone (an NSAID). (56) All studies demonstrated Flavay® protects the inert hyaluronidase from activation. (Hyaluronidase also breaks down the hyaluronic acid in connective tissue.) Researchers noted Flavay® has both anti-inflammatory and anti-allergic activity. (3,35,56,78,146)

Flavay® significantly inhibited formation of pro-inflammatory cytokines, interleukin 1-beta, and tumor necrosis factoralpha. (280)

The anti-inflammatory effects of Flavay® may be due to inhibition of peroxide generation by macrophages. (272,278,279)

Flavay® inhibits lipoxygenase (LOX) and cyclooxygenase (COX). (230)

Flavay® enhanced IL-2 production by mitogen-stimulated splenocytes, decreased production of interleukin 6, and increased the cytotoxicity of natural killer cells. (318)

Two months of Flavay® significantly improved T- and B-cell function. (308)

Flavay® is shown to slow progression of degeneration and stabilizes microcapillaries in the retinal membranes. For this reason, Flavay® should be part of the daily nutritional regimen of every aging person (and most especially every diabetic person).

I started getting night vision problems and so I really didn't want to drive at night. Halogen headlights were a problem but with Flavay my vision is so much better that I can even read the license plate on the oncoming car. My wife, too, her vision has improved. —Mr. D.T.*

Flavay has really helped with my glaucoma. After a few weeks my doctor was surprised because my numbers went down. —Ms. Yvonne B.*

I’ve got three of us taking Flavay, all three of us got better from glaucoma. I’m 82 and a healthy man and I still act like one. I take two Flavay per day. —Mr. Harvey S.*

After 2-3 weeks of taking Flavay I can tell a distinct difference for my eyes. Now, my stainless steel refrigerator looks normal, I don't see irritating waves and or need to blink as before. It's such an easy way for me to gauge what Flavay is doing for my eyes. Also, I see less of a halo around light. I can tell a distinct difference. I'm delighted to see a difference in my skin, too. My aged skin looks a lot better. It's a quality difference in my skin. And I see a huge difference in my mother's skin, a softness that it didn't have before. —Ms. Jane F.*

I was skeptical but desperate when I first ordered Flavay for my diabetic retinopathy. In less than one month the Flavay has produced a dramatic improvement in my condition. My eyes clear as soon as I take my morning dose. I am a doctor of pharmacy and had never heard of your product but you bet I will spread the word... Thank you for saving my vision. The laser surgery just made it worse and my doctor had all but given up so I searched the web for a remedy and found your product. Flavay is remarkable! —Dr. H.H.*

After taking Flavay and Flavay Plus (about four months) my vision is more clear, so much so that I can drive a car and even read a newspaper. Macular degeneration may have etched areas of my retina and I still have to move my eyes around to find spots where I can see the best—but even that has improved a little. I can hardly believe my improvement. I’m astounded that something so simple, strengthening the capillaries in the eyes, has meant so much improvement. —retired medical doctor*

My mom says she feels better and so she stops taking Flavay and Flavay Plus, and then she notices her vision starts getting worse and her memory starts slipping, so she gets back on Flavay and Flavay Plus. She loves what they do for her. —Ms. X.Y.*

I have diabetic retinopathy and for about a year I was blind in one eye, but now I can see out of that eye. Not well enough to read, but improving, so I'll keep taking Flavay and Flavay Plus, currently taking 2 Flavay and 4 Flavay Plus. Did you know that these products are the only ones out there which help my condition, the only ones, and I'll keep taking them. —Mr. Mark M.*

I have been using your product (Flavay) for over a year now and I have found it quite useful for diabetic retinopathy. My right eye is almost blind and my left has very little vision. Even so your product has returned some vision to my eyes. —Dr. F.R.H.*

Flavay and Flavay Plus are helping my wife's eyes. She picked out a Cessna 350 in the sky lately. She hasn't been able to do that until now. —Mr. J. McDonald*

My friend and neighbor has been giving me Flavay bottles for some months because I would tell him when I was out of capsules. I've been using them. I have noticed improvements, especially with my vision. —Mr. R.F.*

I have tried everything else and your Flavay really helps my eyesight. I was having trouble seeing at night and now I don't have that problem anymore. I love Flavay. I also had a blown knee that they had wanted to do surgery on and now I don't have to. I love the Flavay, I really like it! —Ms. T.K.*

I have found Flavay to be a wonderful product. I buy it for my mum's eyes, but we also notice it improves her cognitive function. —Ms. N.S.*

I can read three lines up on the eye chart since taking Flavay and Flavay Plus for my retinopathy! (83-year-old customer whose eye-doctor's office called to receive a Flavay brochure. The doctor's nurse was laughing and saying, “Whatever your product is, it's good!”) —Ms. Daisy B.*

Flavay has so dramatically improved my vision that my son has arranged for me to have a new puppy! I'm a dog lover but when my dog died seven years ago I wouldn't have a new one because I couldn't see well enough to take care of it. —Ms. Daisy B.*

I purchased Flavay for my mother with advanced retinopathy. After taking Flavay her doctor was totally taken aback by what he found, her vision test had improved by 3 lines. We give thanks to the Lord for making this product available —Ms. Judy E.*

* Results vary by person and are not guaranteed. NOTE: We do not compensate for our endorsements and testimonials. We do not consider paid testimonials to be nearly as valuable as comments from customers who were not compensated and yet liked the products so much they gave their testimonials anyway.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.