The Complex Molecular Composition of Flavay

Molecular Composition of Flavay

The Complex Molecular
Composition of Flavay®

Unlike single-molecule nutrients, the molecules in Flavay® are very complex and require specialized knowledge and technology in order to be accurately identified and quantified.

In the huge and very diverse category of 20,000 flavonoids (and its much larger parent category, polyphenols), only the specific group of molecules in Flavay® are found to bind to collagen proteins and make vessels stronger. (2-4,89,178)

Flavay® is Not a Bioflavonoid

Bioflavonoids do not bind to collagen proteins. Bioflavonoids are made of a different species of molecule known as "flavonols" (note the "o"). (2-4,89,178)


Flavay® is Unique

Flavay® consists of molecules known as flavanols (note the "a")—and only in a highly specific form. Flavay® consists of organic groups of one flavanol molecule bonded together in groups of three, known as "flavan-3-ols," which have bonded into small complexes of two, three, four and five (but no larger) clusters, and retained in their naturally-occurring acid nutrients.

Only the specific small complexes of flavan-3-ol molecules in Flavay® bind to collagen proteins and make vessels stronger. (1,2,18,19,89)

Large proanthocyanidins are antinutritive, unsafe in large doses, used in manufacturing exo-friendly plastics, adhesives and resins, and tanning leather. Small, oligo, proanthocyanidins strengthens collagen, improves circulation, reduces inflammation, terminates free radicals, protects cells from oxidation. Singles, flavan-3-ol complexes, very nutritive but only when retained along with its organic small-molecule partners.

Greater than the sum of its parts.

The science of manufacturing Flavay® is complex. Where the single flavan-3-ol molecular groups are highly beneficial, the same molecules are nonnutritive when isolated from their natural partners. So, organic groups of single and small-clusters of specific molecules are selectively preserved while antinutritive large-clusters of molecules are removed. Organic acids are retained to preserve bioactivity in the otherwise highly-perishable molecular complexes.

Small Molecular Size is Important

Large Molecules Must Be Removed for Effectiveness and Safety

Flavay® is uniquely formulated to remove large, antinutritive proanthocyanidins. Flavay® consists of only the small organic clusters of monomers (1), dimers (2), trimers (3), tetramers (4) and pentamers (5)—and no larger.

Organic Acids

Flavay® retains small amounts of other substances called organic acids, including caffeic acid, cinnamic acid, fumaric acid, gallic acid, vanillic acid, ferulic acid, protocatechuic acid, taxifolin, resveratrol and related substances. These "minor" organic acids significantly contribute to the beneficial effects of Flavay®.

Flavay® is a unique formulation of singles and small proanthocyanidins retained in their naturally-occurring acid nutrients, and has been awarded many patents for manufacturing and for vascular protection since 1948.

Only Small Proanthocyanidins
Are Safe and Effective

Oligo means few or small.

Only the small (2-5) clusters of molecules are small enough to fit between collagen fibrils and gently protect delicate tissues. (Clusters of 6+ are too large and their affinity for proteins is too strong to be healthful.)

Genesis: Carbocation: the single flavanol before it irreversibly becomes a single catechin, a single epicatechin, or part of a proanthocyanidin cluster. Catechin: the single flavanol after it irreversibly became a single catechin, not bonded as OPCs. Epicatechin: the single flavanol after it irreversibly became a single epicatechin, not bonded as OPCs.
Dimer: two irreversibly bonded catechins and/or epicatechins Trimer: three irreversibly bonded catechins and/or epicatechins.
OPCs: oligomeric proanthocyanidins are clusters of dimers, 2, trimers, 3, tetramers, 4, and/or pentamers, 5.

Large Proanthocyanidins
Are Ineffective, Unsafe and Antinutritive

Large proanthocyanidins also bind to collagen proteins. But the large clusters of molecules (6+) are so powerful that they crush where the small clusters (2-5) gently stay in check with the delicacy of the tissues they protect. The large proanthocyanidin molecules cannot pass the intestinal tract into the blood because they are too large to fit between collagen fibrils and unable to repair decayed collagen. (3,4)

Large proanthocyanidins are antinutritive because they bind to dietary fiber or proteins and prevent absorption of useful nutrients. (192-194,246)

Large proanthocyanidins are ineffective and antinutritive. (192-194)

Large proanthocyanidins are known as "tannins" and were traditionally used for tanning leather before natural tanning materials were replaced by chemicals. Today, the large proanthocyanidins are used in production of eco-friendly plastics, resins and adhesives. (195,196)

Large proanthocyanidins are clusters of hexamers, 6, or larger.

No Industry Standard for Proanthocyanidins

Consumers need to know there is no American industry standard for accurately identifying and quantifying dietary supplements sold as proanthocyanidins (or, procyanidins). The result is widespread confusion and misunderstanding. Suppliers of grape seed and pine bark extracts use various and unproven manufacturing processes so there are widespread differences in the products.

A review of research studies reveals the problem is enormous. Comparative analyses conducted at the University of British Columbia found commercially-produced proanthocyanidins “differed substantially... shown to be only 7.2% similar... raising questions about its quantification in units of [antioxidant] activity” and confirming there is no standard for proanthocyanidins in the marketplace. (179)

Most producers of grape seed extracts and pine bark extracts leave the large proanthocyanidin molecules (tannins) in their products in order to bulk up the weight and then allow the consumer to wrongly believe they are consuming small molecule (oligomeric) proanthocyanidins (or, OPCs).

Another problem appears where only single complexes are used. A published study discovered certain commercially-produced proanthocyanidins were totally ineffective because they were comprised of exclusively single complexes rather than small-cluster complexes of proanthocyanidins. (428)

Unfortunately, because there is no industry standard and therefore absolutely no verification process, there is as much confusion as there are commercial opportunists in this category.

The Original and Only True Standard
for Proanthocyanidins Since 1947

Flavay - International and U.S. Patents and Clinically Proven

Patented Manufacturing Processes

Authenticity ∙ Purity ∙ Effectiveness

More than 70 years of solid scientific research, patents and clinical studies, rigorous manufacturing controls and comprehensive identity-testing safeguard quality and consistency of Flavay®.

Flavay® is the name you can trust for the original, patented and perfected, pure and unadulterated, small-cluster oligomeric proanthocyanidins complex manufactured in France where it has been tested as a medicine for safety and validated by the French Ministry of Health and approved for over-the-counter use.

My joints aren't hurting and my back feels better and I'm even able to work better. I'll tell you, I can feel Flavay! —Ms. C.V.*

I have lupus and taking Flavay enables me to move. I'm not able to do without it. I've been taking it for more than a decade and my skin looks younger, in fact people think I'm my kid's sister. —Ms. L.B.*

After about 6 to 9 weeks it made a profound difference. I’ve lost inches in swelling. I cannot say enough about Flavay! Over the years, I’ve stopped and started again and found for vascular and lymphatic edema, nothing is better than Flavay. —Ms. Marie D.*

I just want to say that I love Flavay. When I stop taking it, the pain comes right back. —Mr. Mark H.*

I feel flexibility, while tying my shoes, wow! The simple things work better. I feel a general sense of wellbeing with Flavay. —Mr. Peter M.*

I love your product called Flavay. I feel it does the job! —Mr. Robert B.*

I've got to have my Flavay. Keeps me going. Keeps me young. 4 Flavay every day. —Mr. C.S.*

I had a terrible accident where I fell 20 feet and injured my back and it was really bad. I went from a wheelchair to a cane and now I'm mowing the lawn. Flavay shrank the protruding disk so I could stand up straight again. I've referred many many people to your products, and it worked for them too. —Mr. Dave T.*

Flavay is a product I cannot stop taking. When I stopped taking it for a couple of weeks, my neuropathy and arthritis pain come raging back. So I started again on Flavay and the pain is almost completely gone. —Ms. Elsa D.*

I started taking Flavay for arthritis pain and I feel so much better! I'm so thrilled! —Ms. Susan S.*

After taking Flavay for just a week, my sister is doing things she couldn’t do before, such as bending over to pick things up off the floor. —Mr. Joe C.*

The puffiness in my legs is so much better. Oh my gosh this Flavay is great! —Ms. Joan G.*

Your Flavay really helps my husband's chronic pain syndrome and we're almost out! Please ship asap! —Ms. S.W.*

I was taking Flavay for pain and mobility. Now I take Flavay as much for the benefits to my skin as for joint pain. —Mr. H.S.*

Oh, I just love Flavay! I feel so much better! —Ms. Y.L.*

I can’t even tell you how much I appreciated finding your product Flavay and the incredible results and relief I have gotten from taking it... I skeptically ordered two bottles... And low and behold, it works. I read that I could take more than 2 that some people had to take 4 or 5 at a time, so I did, hoping and praying, and my prayers were answered. To say thank-you is an understatement, and I have been able to stop all other pain meds. I honestly was on a one way road to nowhere, now I am free again..a feeling I haven’t had in over 12 years. Thank-you!!!!!!!!!!!!!!! —Ms. Beth B.*

I am a nutritionist and I have referred two of my clients to take Flavay. Both of my clients have raved about the product. One of my clients has a problem with circulation and she said Flavay really works for her. —Mr. John H.*

I've got to have my Flavay. Keeps me going. Keeps me young. 4 Flavay every day. —Mr. C.S.*

My neighbor is so pleased with Flavay telling me how much better she feels. She has heart problems and taking 2 Flavay per day she has so much energy again and her color is better too. —Ms. C.V.*

I have tried everything else and your Flavay really helps my eyesight. I was having trouble seeing at night and now I don't have that problem anymore. I love Flavay. I also had a blown knee that they had wanted to do surgery on and now I don't have to. I love the Flavay, I really like it! —Ms. T.K.*

I start feeling pain in my joints after a few days of not taking Flavay. —Mr. Mark H.*

My daughter has rheumatoid arthritis in her knees and years ago Flavay had really helped her, so I want to order some more for her. —Ms. K.M.*

For several years I took Flavay for fibromyalgia and it really worked and I felt so much better. Now I need to start again. —Ms. C.H.*

I love your product called Flavay. I feel it does the job! —Mr. R.H.*

I have had joint pain in my hips for a couple years. I have been taking Flavay for about 30 days and I realized I don't have hip joint pain when laying down or sitting for long periods! I will continue to take it daily. —Ms. M.H.*

Thank you so much. I'm desperate!! 😊 Haven't taken them (Flavay and Flavay Plus) for a few months and can tell the difference! —Ms. S.A.*

Since I started taking Flavay I felt so good and I'm hoping to keep getting better. I started taking Flavay for my knee but since I started taking Flavay I've cut way back on asthma meds. The medication affects my brain badly. I want to control asthma instead of it controlling me. Flavay is a big help, I am so happy! —Ms. J.I.*

I began giving my daughter Flavay Plus for ADD and then I decided to add Flavay for my daughter's allergies. I want to tell you, the Flavay works like a charm for my daughter’s allergies. She is 6 years old, and when we ran out of capsules this week she told me, “You've got to get more Flavay!” —Ms. S.S.*

I just wanted to write and say WOW... I was so skeptical of your product at first and really had a negative attitude when I started taking it. I am a 40 yr old female with anxiety, mild ADHD and a host of arthritis and inflammation issues. It was a struggle for me to get out of bed everyday and focus on what needed to be done. I had no focus, no attention span, no energy, and no desire to do anything. About a week into taking Flavay and Flavay Plus, I started noticing that I could think a little clearer. My rheumatoid arthritis flare-ups weren't so bad, though I still have them. feeling better, and having more energy. I never thought I would feel like my old self again. I don't know exactly how you do it,...but this stuff works! I am telling all of my friends to try it because you've given me my old life back! Thank you! —Ms. L.A.*

I am not one to review products, but i can't deny some of the benefits i've experienced using both your biomor curcumin and flavay products. I've been taking both for a few months now, and the two major benefits i've noticed are 1) joint strength and mobility (for workouts) as i am lifting much heavier weights without injury 2) I am a paroxsymal Afib sufferer, and my episodes have gone from 2-3 per week down to zero (most weeks). This can't just be a coincidence. I think there is definitely something in your formulas that stop inflammation and get your body in balance and healing itself. —Mr. B.V.W.*

I damaged both knees in a motor cycle accident, (mostly pain and swelling ). I don't even think about my knees anymore , its been that long since they have caused me any pain. I have been taking Flavay for 3 Years, I had my right wrist diogonsed with carpal tunnel syndrome, ( hand and arm going to sleep) after having surgery on the left arm years ago, did not have the time for surgery( 3 week recovery) but since Flavay no more pain , the pin and needles are gone so I don't wake up in the middle of the night with my arms and hands bothering me. The amazing thing about this product it can take care of problems you just forgot you had, (or just learned to live with) . Now forget about them because the pain is gone. —Mr. B. Hall*

I really notice a difference when taking Flavay Plus, both in inflammation and in my stress levels. —Ms. W.L.*

I'm real happy about Flavay. It seems to have a positive effect on my lymph system. —Ms. R.M.*

I just love Flavay. If you ever need do a commercial, I’ll be happy to do it! —Ms. Linda M.*