Cortisol is a double-edged sword. We need it to adapt to stress but when levels remain too high, cortisol causes brain fog and suppresses the immune system. Over the long term, elevated cortisol levels lead to serious health problems.
Cortisol affects mood and behavior and disrupts memory and recall. Research shows cortisol has significant interactions with the neurotransmitters, neuropeptides, and brain circuits that are associated with depressive symptoms. (R2)